I had an interesting discovery recently. I had a transplant April of 2018 because of PSC. We’ve been slowly reducing my medications as time goes on, with no signs of reoccurrence.
On April of 2019, we tried to go down to just one medication, and suddenly I had elevated liver enzymes… typical of PSC. My doctor immediately had me resume the last medication I stopped, and all was well within a week.
I saw in his notes after that he resumed the medication for “prevention of PSC reoccurrence.” My first thought - why didn’t we try that before transplant? He didn’t really have an answer.
The medication was Cellcept…500mg 2 x a day. That’s an immunosuppressant I thought only to prevent organ rejection. Now, no one knows for sure… but it’s thought that PSC was an autoimmune disease. So, slightly suppressing the the immune system with that alone, might have prevented further damage…and maybe I wouldn’t have gotten to the point where I needed a transplant!
Just my two cents… maybe something to share with your doctors.