Hello everyone, I’m a 24 years old man from Brazil.
I was diagnosticated with UC (proctitis) in 2012, due to a flare up that cause me diarrhea and presence of mucus and blood on my stools. In this occasion I’m being treated with mesalazine for some months and, since then, I have been in remission. However, in the middle of last year, I have an alteration in my stool consistency /frequency and a vague RUQ pain, what leads me to have some tests like colonoscopy and LFT’s. Colonoscopy were normal, no signal of UC, but the stool consistency remains altered to this day, the RUQ pain too. In the first LFT, GGT and ALT are slightly elevated, which didn’t cause me any concern. But the LFT’s are progressively increasing since that (dates and values below) and due to that, my GI is suspecting of PSC. I had an ultrasound, a general MRI and a MRCP, all clear. Blood tests for autoimmune markers are clear too. Billirubins are in the normal range. The doctor said that we have to wait a few more months before perfoming liver biopsy, but these alterations are driving me crazy. When and why is advised to do liver biopsy? What are my “chances” of having PSC? Have any of you ever been in a similar situation?
Dates and LFT’s:
07/2018 – GGT: 126; ALT: 55; AST: 33
10/2018 – GGT: 161; ALT: 66; AST: 36; ALP: 93
12/2018 – GGT: 195; ALT: 69; AST: 36
01/2019 – GGT: 195; ALT: 92; AST: 40; ALP: 130
GGT: 7 – 58
ALT: 11 – 45
AST: 11 – 39
ALP: 27 – 100
Thank you for accepting me on this forum and sorry for any grammar error.