Hey there! That’s great your daughter was able to get a vanco prescription. I’ve been taking vanco for my PSC since January 2018 and it’s the healthiest I’ve ever felt!
Brand and dose is very important when taking vanco for PSC. Both are patient-specific, so it might take some trial and error to find the right brand and dose that works for your daughter.
Regarding brand, from personal experience and from what I’ve heard in the PSC community, ANI Pharmaceuticals seems to be the most effective. Some people appear to respond well to Lupin if ANI isn’t accessible. Other brands like Akorn and Alvogen seem to not work as well. (I was accidentally put on Akorn a few years ago and completely flared until I was put back on ANI).
Regarding dose, the standard dose is 500mg 3x per day (a total of 1,500mg per day. However, some patients need a higher or smaller dosage.
The Stanford protocol suggests starting at 500 mg 3x/day for patients who weigh more than 30 kg and to increase the dosage until the patient’s symptoms normalize. For children under 18 who weigh less than 30 kg, the Stanford protocol suggests 50 mg/kg/day.
Lastly, many patients feel a difference with vanco within 3 months. Some respond in a matter of days. For myself, I responded right at the 6-week mark. So if she doesn’t feel better in a few weeks, give it at least 3 months to see how she’s feeling.
Please keep us posted! I’d love to hear how she’s doing after 3 months. I’m very passionate about vanco for PSC, so let me know if you have any questions at all!